Massively parallel reporter assays across five cell types identify thousands of causal, noncoding regulatory variants among 220,000 loci, revealing diverse regulatory mechanisms shaping complex traits and disease.
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The design of Web streams predates async iteration in JavaScript. The for await...of syntax didn't land until ES2018, two years after the Streams Standard was initially finalized. This timing meant the API couldn't initially leverage what would eventually become the idiomatic way to consume asynchronous sequences in JavaScript. Instead, the spec introduced its own reader/writer acquisition model, and that decision rippled through every aspect of the API.